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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
11.82
Human Site:
S18
Identified Species:
20
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S18
V
R
T
G
D
M
E
S
Q
R
D
L
S
L
V
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S18
V
R
T
G
D
M
E
S
Q
R
D
L
S
L
V
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S18
V
R
T
G
D
M
E
S
Q
R
D
L
S
L
V
Dog
Lupus familis
XP_538923
388
42549
S60
A
A
N
G
A
V
G
S
Q
R
D
R
S
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
R35
L
Q
R
R
E
Q
E
R
Q
I
E
V
E
R
R
Rat
Rattus norvegicus
NP_001101670
340
38058
R35
L
Q
R
R
E
Q
E
R
Q
M
E
V
E
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
G22
P
Q
G
G
E
G
P
G
P
L
P
E
R
L
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
L28
V
K
V
P
E
S
V
L
R
R
D
Q
A
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
N20
L
E
R
L
N
K
R
N
K
D
R
Q
N
Y
L
Honey Bee
Apis mellifera
XP_001120828
342
39209
R18
L
P
D
R
I
T
K
R
D
R
E
R
K
N
V
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
K30
I
N
G
K
D
I
K
K
D
R
I
P
A
G
L
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
R18
K
H
Q
A
M
L
D
R
L
S
N
R
H
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
Q18
E
T
L
D
P
A
L
Q
K
K
H
H
D
M
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
100
53.3
N.A.
13.3
13.3
N.A.
13.3
N.A.
N.A.
20
N.A.
0
13.3
0
13.3
P-Site Similarity:
100
100
100
60
N.A.
46.6
46.6
N.A.
26.6
N.A.
N.A.
53.3
N.A.
40
33.3
0
46.6
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
8
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
29
0
8
0
15
8
36
0
8
0
0
% D
% Glu:
8
8
0
0
29
0
36
0
0
0
22
8
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
36
0
8
8
8
0
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
8
8
0
0
% H
% Ile:
8
0
0
0
8
8
0
0
0
8
8
0
0
0
0
% I
% Lys:
8
8
0
8
0
8
15
8
15
8
0
0
8
0
0
% K
% Leu:
29
0
8
8
0
8
8
8
8
8
0
22
0
36
29
% L
% Met:
0
0
0
0
8
22
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
8
8
0
8
0
0
8
0
0
8
0
8
8
0
% N
% Pro:
8
8
0
8
8
0
8
0
8
0
8
8
0
0
0
% P
% Gln:
0
22
8
0
0
15
0
8
43
0
0
15
0
8
8
% Q
% Arg:
0
22
22
22
0
0
8
29
8
50
8
22
8
22
15
% R
% Ser:
0
0
0
0
0
8
0
29
0
8
0
0
29
0
8
% S
% Thr:
0
8
22
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
29
0
8
0
0
8
8
0
0
0
0
15
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _